Heavy Metal Toxicity and Therapeutics

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Heavy Metal Toxicity

Heavy metals are metallic elements which have a high atomic weight and a density much greater (at least 5 times) than water. There are more than 20 heavy metals, but four are of particular concern to human health: lead (Pb), cadmium (Cd), mercury (Hg), and inorganic arsenic (As). According to the U.S. Agency for Toxic Substances and Disease Registry. These four heavy metals are four of the top ...

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Heavy Metal Toxicity

In general, irritable health concern related to heavy metal (accumulation) might be mainly divided into 2 types, i.e. heavy metal poisoning caused by excessive extrinsic exposure and genetic disorders such as Wilson disease (as reviewed by Osredkar et al. in this issue). As for the former type, unlike the latter one, it can be said that the health damage spread with the development of the civil...

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Heavy Metal Toxicity and ADHD

Cumulative evidence shows that the long-term prognosis for ADHD is poor, with higher rates of persistent psychiatric problems (Shekim et al., 1990), neurocognitive difficulties (Murphy et al., 2002), and academic struggles (Ratey et al., 1992). Many theoretical models have been put forward to explain the cause of ADHD (Barkley, 1997); however, it is largely recognized that it is a heterogeneous...

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Speciation in Metal Toxicity and Metal-Based Therapeutics

Metallic elements, ions and compounds produce varying degrees of toxicity in organisms with which they come into contact. Metal speciation is critical to understanding these adverse effects; the adjectives "heavy" and "toxic" are not helpful in describing the biological properties of individual elements, but detailed chemical structures are. As a broad generalization, the metallic form of an el...

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Plant growth, pigment concentration, biochemical parameters and uptake of heavy metals were determined for Brassica juncea L. in response to cadmium and lead stress. The plant exhibited a decline in growth, chlorophyll content and carotenoids with Cd and Pb but Cd was found to be more detrimental than Pb treatment in B. juncea. The protein content was decreased by Cd (900 μM) to 95% and 44% by ...

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ژورنال

عنوان ژورنال: Journal of Drug Metabolism & Toxicology

سال: 2013

ISSN: 2157-7609

DOI: 10.4172/2157-7609.1000e120